(±)-Equol

Research use only, not for human use.

Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora.

Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora.The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50= 85 and 65 nM for human ERα and ERβ, respectively) is similar to that of genistein but exceeds that of daidzein.(S)-Equol preferentially binds ERβ (Ki= 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki= 6.41 nM).(S)-equol is also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies.

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Others

Other Targets

ERα; ERβ

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94105-90-5

242.3

C15H14O3

98%

DMSO : ≥ 100 mg/mL; 412.76 mM

C1C(COc2c1ccc(c2)O)c1ccc(cc1)O

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(-20℃)

With Ice Pack

≥ 2 years