(S,R,S)-AHPC-PEG4-N3

CAS No. 1797406-81-5

(S,R,S)-AHPC-PEG4-N3 ( VH032-PEG4-N3; VHL Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 4 )

Catalog No. M26950 CAS No. 1797406-81-5

(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 45 Get Quote
5MG 75 Get Quote
10MG 107 Get Quote
25MG 177 Get Quote
50MG 266 Get Quote
100MG 410 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    (S,R,S)-AHPC-PEG4-N3
  • Note
    Research use only, not for human use.
  • Brief Description
    (S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.
  • Description
    (S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.(In Vitro):E3?ligase Ligand-Linker Conjugates 4 together with JQ1 triggers the intracellular destruction of BET proteins.
  • Synonyms
    VH032-PEG4-N3; VHL Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 4
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ATP-sensitive potassium (KATP) channels
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1797406-81-5
  • Formula Weight
    689.8
  • Molecular Formula
    C32H47N7O8S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)COCCOCCOCCOCCN=[N+]=[N-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.L?ffler C, et al. Pharmacological characterization of the sulphonylurea receptor in rat isolated aorta. Br J Pharmacol. 1997 Feb;120(3):476-80.
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