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(S)-MCPG
CAS No. 150145-89-4
(S)-MCPG( —— )
Catalog No. M33187 CAS No. 150145-89-4
(S)-MCPG ((+)-MCPG) is a class I/II metabotropic glutamate receptors (mGluRs) antagonist that blocks spatial learning and long-term enhancement of the dentate gyrus in vivo in rats, and can be used to study neurological disorders.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 46 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product Name(S)-MCPG
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NoteResearch use only, not for human use.
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Brief Description(S)-MCPG ((+)-MCPG) is a class I/II metabotropic glutamate receptors (mGluRs) antagonist that blocks spatial learning and long-term enhancement of the dentate gyrus in vivo in rats, and can be used to study neurological disorders.
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Description(S)-MCPG ((+)-MCPG) is a potent group I/II metabotropic glutamate receptor(mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371). (S)-MCPG can be used for the study of the function of mGluRs in spatial learning.
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In Vitro——
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In VivoAnimal Model:Male Lister-Hooded rats in the learning of the Morris water mazeDosage:20 μg Administration:Intraventricular injection; 20 μg; 4 days Result:Impaired the performance of rats in the spatial version of the Morris water maze, but 1/10 of this dose did not.
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Synonyms——
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PathwayNeuroscience
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TargetGluR
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RecptorGluR
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Research Area——
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Indication——
Chemical Information
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CAS Number150145-89-4
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Formula Weight209.2
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Molecular FormulaC10H11NO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?1M NaOH : 22 mg/mL (105.16 mM; ultrasonic and adjust pH to 11 with NaOH)
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SMILESC[C@@](N)(C(O)=O)c1ccc(cc1)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bernadett Boda, et al. Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome. Eur J Neurosci. 2014 Apr;39(7):1130-7.?
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