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(Rac)-Acolbifene
CAS No. 151533-34-5
(Rac)-Acolbifene ( EM-343; (Rac)-EM-652 )
Catalog No. M26408 CAS No. 151533-34-5
(Rac)-Acolbifene is the racemic form of EM652 (estrogen receptor antagonist), has anti-estrogenic and estrogenic activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 111 | Get Quote |
|
| 10MG | 178 | Get Quote |
|
| 25MG | 407 | Get Quote |
|
| 50MG | 599 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product Name(Rac)-Acolbifene
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NoteResearch use only, not for human use.
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Brief Description(Rac)-Acolbifene is the racemic form of EM652 (estrogen receptor antagonist), has anti-estrogenic and estrogenic activities.
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Description(Rac)-Acolbifene is the racemic form of EM652 (estrogen receptor antagonist), has anti-estrogenic and estrogenic activities.(In Vitro):In T-47D cells, (Rac)-Acolbifene (0.110 nM) inhibits cell growth with an IC50 value of 0.110 nM.(In Vivo):In ovariectomized mice, (Rac)-Acolbifene (7.5 nM, 75 nM; oral) shows shows 63% and 84% antiuterotrophic inhibitions, respectively.
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SynonymsEM-343; (Rac)-EM-652
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PathwayOthers
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TargetOther Targets
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RecptorFGFR1; FGFR2; FLT3; PDGFR; VEGFR1; VEGFR2; VEGFR3
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Research Area——
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Indication——
Chemical Information
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CAS Number151533-34-5
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Formula Weight457.6
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Molecular FormulaC29H31NO4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=C(C(Oc2cc(O)ccc12)c1ccc(OCCN2CCCCC2)cc1)c1ccc(O)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tovar C, et al. Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy. Cell Cycle. 2010 Aug 15;9(16):3364-75.
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