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(Rac)-AMG8379

CAS No. 1641574-26-6

(Rac)-AMG8379 ( (Rac)-AMG8380 )

Catalog No. M26409 CAS No. 1641574-26-6

(Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 264 Get Quote
5MG 403 Get Quote
10MG 592 Get Quote
25MG 888 Get Quote
50MG 1242 Get Quote
100MG 1701 Get Quote
500MG 3402 Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    (Rac)-AMG8379
  • Note
    Research use only, not for human use.
  • Brief Description
    (Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).
  • Description
    (Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).
  • Synonyms
    (Rac)-AMG8380
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ATF4; ATF6; ERK; GRP78; MMP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1641574-26-6
  • Formula Weight
    543.9
  • Molecular Formula
    C25H16ClF2N3O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=S(NC1=NOC=C1)(C2=CC(C=CC(N3C4=CC(F)=C(C=C4OC)C5=CC(Cl)=CC(F)=C5)=O)=C3C=C2)=O.[Racemate]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang B, Han H, et al. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. Biochem Pharmacol. 2016 Mar 15;104:8-18.
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