(R)-ZINC-3573

CAS No. 2089389-15-9

(R)-ZINC-3573( —— )

Catalog No. M34478 CAS No. 2089389-15-9

(R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe that activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 61 Get Quote
10MG 92 Get Quote
25MG 210 Get Quote
50MG 316 Get Quote
100MG 447 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    (R)-ZINC-3573
  • Note
    Research use only, not for human use.
  • Brief Description
    (R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe that activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.
  • Description
    (R)-ZINC-3573 is a selective Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist with an EC50 value of 740 nM. (R)-ZINC-3573 can be used as a MRGPRX2 probe for the research of pain and itch.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    MRGPR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2089389-15-9
  • Formula Weight
    307.39
  • Molecular Formula
    C18H21N5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (162.66 mM; Ultrasonic (<60°C)
  • SMILES
    CN(C)[C@@H]1CCN(C1)c1cc(nc2ccnn12)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lansu K, et al. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol. 2017 May;13(5):529-536.?
molnova catalog
related products
  • Hexadecanedioic acid

    Hexadecanedioic acid is a common saturated fatty acid found in animals plants and microorganisms. It has antitumor activity.

  • Leachianol F

    Leachianol F is a natural product for research related to life sciences.

  • Neoschaftoside

    Neoschaftoside has antioxidant activity.