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(R)-HH2853
CAS No. 2202678-06-4
(R)-HH2853( —— )
Catalog No. M36497 CAS No. 2202678-06-4
(R)-HH2853 is a potent EZH2 inhibitor with an IC50 <100 nM for EZH2-Y641F.(R)-HH2853 has anticancer and antitumor activity and can be used in autoimmune diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 506 | Get Quote |
|
| 5MG | 751 | Get Quote |
|
| 10MG | 1064 | Get Quote |
|
| 25MG | 1536 | Get Quote |
|
| 50MG | 2070 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product Name(R)-HH2853
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NoteResearch use only, not for human use.
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Brief Description(R)-HH2853 is a potent EZH2 inhibitor with an IC50 <100 nM for EZH2-Y641F.(R)-HH2853 has anticancer and antitumor activity and can be used in autoimmune diseases.
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Description(R)-HH2853 is a mutant EZH2 inhibitor with an IC50 of <100 nM for EZH2-Y641F. (R)-HH2853 can be used for cancer and autoimmune diseases (WO2018045971A1; compound 201).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorHistone Methyltransferase
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Research Area——
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Indication——
Chemical Information
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CAS Number2202678-06-4
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Formula Weight611.66
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Molecular FormulaC31H36F3N7O3
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Purity>98% (HPLC)
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Solubility——
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SMILES[C@@H](C)(C=1N2C(=C(C=C2)C3=CC=C(C)N=N3)C=C(C(NCC4=C(OC)C=C(C)NC4=O)=O)C1C)N5CCN(CC(F)(F)F)CC5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xuxing Chen, et al. Pyrido five-element aromatic ring compound, preparation method therefor and use thereof. WO2018045971A1.
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