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(R)-Elagolix
CAS No. 834153-87-6
(R)-Elagolix( NBI-56418 )
Catalog No. M24824 CAS No. 834153-87-6
(R)-Elagolix is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively.?
(R)-Elagolix is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 41 | In Stock |
|
| 5MG | 65 | In Stock |
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| 10MG | 102 | In Stock |
|
| 25MG | 178 | In Stock |
|
| 50MG | 312 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | 659 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(R)-Elagolix
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NoteResearch use only, not for human use.
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Brief Description(R)-Elagolix is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively.?
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Description(R)-Elagolix is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively.?administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses.
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In Vitro——
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In Vivo——
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SynonymsNBI-56418
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PathwayOthers
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TargetOther Targets
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RecptorGnRHR
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Research Area——
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Indication——
Chemical Information
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CAS Number834153-87-6
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Formula Weight631.59
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Molecular FormulaC32H30F5N3O5
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (158.33 mM)
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SMILESCC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)C[C@@H](C3=CC=CC=C3)NCCCC(=O)O)C4=C(C(=CC=C4)OC)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Carr B, et al. Elagolix, an oral GnRH antagonist, versus subcutaneous depot medroxyprogesterone acetate for the treatment of endometriosis: effects on bone mineral density. Reprod Sci. 2014 Nov;21(11):1341-1351.
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