(R)-Elagolix

Research use only, not for human use.

(R)-Elagolix is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively.?

(R)-Elagolix is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively.?administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses.

NBI-56418

Others

Other Targets

GnRHR

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——

834153-87-6

631.6

C32H30F5N3O5

>98% (HPLC)

DMSO:100 mg/mL (158.33 mM)

CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)C[C@@H](C3=CC=CC=C3)NCCCC(=O)O)C4=C(C(=CC=C4)OC)F

——

(-20℃)

With Ice Pack

≥ 2 years