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Home - Products - Neuroscience - GluR - (R)-ADX-47273

(R)-ADX-47273

CAS No. 851881-59-9

(R)-ADX-47273( —— )

Catalog No. M26528 CAS No. 851881-59-9

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 61 Get Quote
5MG 102 Get Quote
10MG 177 Get Quote
25MG 322 Get Quote
50MG 528 Get Quote
100MG 755 Get Quote
500MG 1521 Get Quote
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Biological Information

  • Product Name
    (R)-ADX-47273
  • Note
    Research use only, not for human use.
  • Brief Description
    (R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).
  • Description
    (R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).
  • In Vitro
    (R)-ADX-47273 (ADX-47273 (5)) is a potent mGluR5 positive allosteric modulator with an EC50 for potentiation of 168 nM and a 9-fold shift of the glutamate response curve at 1 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    LIM Kinase (LIMK)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    851881-59-9
  • Formula Weight
    369.372
  • Molecular Formula
    C20H17F2N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (270.74 mM)
  • SMILES
    Fc1ccc(cc1)C(=O)N1CCC[C@H](C1)c1nc(no1)-c1ccc(F)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wu J, Liu S, Fan Z, Zhang L, Tian Y, Yang R. A novel and selective inhibitor of PKC ζ potently inhibits human breast cancer metastasis in vitro and in mice. Tumour Biol. 2016 Jun;37(6):8391-401.
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