(R)-(-)-Rolipram

CAS No. 85416-75-7

(R)-(-)-Rolipram ( R)-Rolipram;(-)-Rolipram )

Catalog No. M16203 CAS No. 85416-75-7

A more active enantiomer of the PDE4 inhibitor rolipram.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 Get Quote
5MG 56 Get Quote
10MG 88 Get Quote
25MG 170 Get Quote
50MG 317 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    (R)-(-)-Rolipram
  • Note
    Research use only, not for human use.
  • Brief Description
    A more active enantiomer of the PDE4 inhibitor rolipram.
  • Description
    A more active enantiomer of the PDE4 inhibitor rolipram; shows 2-10-fold more potent than the S-(+) enantiomer rolipram.Asthma Phase 2 Clinical
  • Synonyms
    R)-Rolipram;(-)-Rolipram
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE
  • Research Area
    Inflammation/Immunology
  • Indication
    Asthma

Chemical Information

  • CAS Number
    85416-75-7
  • Formula Weight
    275.34
  • Molecular Formula
    C16H21NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 49 mg/mL
  • SMILES
    COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3
  • Chemical Name
    2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schneider HH, et al. Eur J Pharmacol. 1986 Aug 7;127(1-2):105-15.
2. Owens RJ, et al. Biochem J. 1997 Aug 15;326 ( Pt 1):53-60.
3. Ohsawa F, et al. Jpn J Pharmacol. 1998 Jun;77(2):147-54.
molnova catalog
related products
  • HA155

    HA155 selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.

  • (+)-Medioresinol Di-...

    (+)-Medioresinol Di-O-β-D-glucopyranoside has strong inhibitory activity of cyclic AMP phosphodiesterase.

  • Tofimilast

    Tofimilast (CP-325366) is a potent, selective PDE4 inhibitor with IC50 of 23, 13 and 13 nM for PDE4A, PDE4B, and PDE4D, respectively.