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(R)-(-)-Rolipram

CAS No. 85416-75-7

(R)-(-)-Rolipram ( R)-Rolipram;(-)-Rolipram )

Catalog No. M16203 CAS No. 85416-75-7

A more active enantiomer of the PDE4 inhibitor rolipram.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (R)-(-)-Rolipram
  • Note
    Research use only, not for human use.
  • Brief Description
    A more active enantiomer of the PDE4 inhibitor rolipram.
  • Description
    A more active enantiomer of the PDE4 inhibitor rolipram; shows 2-10-fold more potent than the S-(+) enantiomer rolipram.Asthma Phase 2 Clinical
  • Synonyms
    R)-Rolipram;(-)-Rolipram
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE
  • Research Area
    Inflammation/Immunology
  • Indication
    Asthma

Chemical Information

  • CAS Number
    85416-75-7
  • Formula Weight
    275.34
  • Molecular Formula
    C16H21NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 49 mg/mL
  • SMILES
    COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3
  • Chemical Name
    2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schneider HH, et al. Eur J Pharmacol. 1986 Aug 7;127(1-2):105-15.
2. Owens RJ, et al. Biochem J. 1997 Aug 15;326 ( Pt 1):53-60.
3. Ohsawa F, et al. Jpn J Pharmacol. 1998 Jun;77(2):147-54.
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