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(E)-SI-2

CAS No. 380537-35-9

(E)-SI-2 ( —— )

Catalog No. M28929 CAS No. 380537-35-9

(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (E)-SI-2
  • Note
    Research use only, not for human use.
  • Brief Description
    (E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2.
  • Description
    (E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks MDA-MB-468 cell growth with an IC50 value of 3.4 nM, but spares normal cells.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    380537-35-9
  • Formula Weight
    265.3
  • Molecular Formula
    C15H15N5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN1C2=CC=CC=C2N=C1N/N=C(C3=NC=CC=C3)\C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.By Wright, George E.; Xu, Wei-Chu From U.S. (2014), US 8796292 B2 20140805.
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