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(1S,2S)-Bortezomib
CAS No. 1132709-14-8
(1S,2S)-Bortezomib( Bortezomib )
Catalog No. M26020 CAS No. 1132709-14-8
(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the proteasome with a Ki of 0.6 nM for 20S proteasome.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 133 | In Stock |
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| 5MG | 258 | In Stock |
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| 10MG | 447 | In Stock |
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| 25MG | 716 | In Stock |
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| 50MG | 972 | In Stock |
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| 100MG | 1305 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(1S,2S)-Bortezomib
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NoteResearch use only, not for human use.
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Brief Description(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the proteasome with a Ki of 0.6 nM for 20S proteasome.
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Description(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the proteasome with a Ki of 0.6 nM for 20S proteasome.(In Vitro):Bortezomib disrupts the cell cycle, induces apoptosis, inhibits NF-κB, and possesses anti-cancer capacity.
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In Vitro——
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In Vivo——
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SynonymsBortezomib
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PathwayProteasome/Ubiquitin
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TargetProteasome
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RecptorNon-cleavable
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Research Area——
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Indication——
Chemical Information
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CAS Number1132709-14-8
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Formula Weight384.24
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Molecular FormulaC19H25BN4O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (130.13 mM)
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SMILES[C@H](CC1=CC=CC=C1)(C(N[C@H](CC(C)C)B(O)O)=O)NC(=O)C=2C=NC=CN2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers. J Med Chem. 2017 Dec 14;60(23):9490-9507.
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