Tebipenem

Research use only, not for human use.

Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria.

Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria.(In Vitro):Tebipenem shows potent activity against B. pseudomallei (MIC50 and MIC90: both 2 mg/L). Tebipenem displays slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin (apparent Km and kcat: 0.8 μM and 0.03 min-1, respectively). Tebipenem shows good activity against S. pneumoniae, with the MIC range of ≤0.25 μg/mL in all of the S. pneumoniae isolates .

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LJC 11036

Microbiology/Virology

Antibiotic

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161715-21-5

383.48

C16H21N3O4S2

>98% (HPLC)

In Vitro:?DMSO : 33.33 mg/mL (86.91 mM)

C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(SC3CN(C3)C3=NCCS3)=C(N2C1=O)C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years