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Mtb-IN-2

CAS No. 2861190-30-7

Mtb-IN-2( —— )

Catalog No. M37211 CAS No. 2861190-30-7

Mtb-IN-2 is a small molecule compound of Mycobacterium tuberculosis (Mtb) with antimicrobial activity and low toxicity that interferes with methionine metabolism processes and can be used to study tuberculosis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	144	Get Quote
5MG	217	Get Quote
10MG	321	Get Quote
25MG	523	Get Quote
50MG	748	Get Quote
100MG	981	Get Quote
500MG	2547	Get Quote
1G	3717	Get Quote

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Biological Information

Product Name

Mtb-IN-2
Note

Research use only, not for human use.
Brief Description

Mtb-IN-2 is a small molecule compound of Mycobacterium tuberculosis (Mtb) with antimicrobial activity and low toxicity that interferes with methionine metabolism processes and can be used to study tuberculosis.
Description

Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murinetuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Microbiology/Virology
Target

Antibiotic
Recptor

Antibiotic
Research Area

——
Indication

——

Chemical Information

CAS Number

2861190-30-7
Formula Weight

308.29
Molecular Formula

C17H12N2O4
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(O)C1=CC=C(C=C1O)NC(=O)C=2N=C3C=CC=CC3=CC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Nawrot DE, et al. Antimycobacterial pyridine carboxamides: From design to in vivo activity. Eur J Med Chem. 2023 Oct 5;258:115617.?

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