RGB-1

CAS No. 930455-91-7

RGB-1( —— )

Catalog No. M37294 CAS No. 930455-91-7

RGB-1, a small molecule that selectively stabilizes the RNA G-quadruplex structure, enhances G-quadruplex-mediated inhibition of RNA translation in mammalian cells and reduces NRAS proto-oncogene expression in breast cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    RGB-1
  • Note
    Research use only, not for human use.
  • Brief Description
    RGB-1, a small molecule that selectively stabilizes the RNA G-quadruplex structure, enhances G-quadruplex-mediated inhibition of RNA translation in mammalian cells and reduces NRAS proto-oncogene expression in breast cancer cells.
  • Description
    RGB-1 is a polycyclic aromatic hydrocarbon molecule and a stabilizer of RNA G-quadruplexes. RGB-1 can promote the inhibition of RNA translation and reduce the expression of NRAS proto-oncogene in breast cancer cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    930455-91-7
  • Formula Weight
    460.49
  • Molecular Formula
    C22H12N4O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1C2=C(N=C3N1CC4=NC=5SC=C(C=6OC=CC6)C5C(=O)N4C3)SC=C2C=7OC=CC7
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Katsuda Y, et al. A Small Molecule That Represses Translation of G-Quadruplex-Containing mRNA. J Am Chem Soc. 2016 Jul 27;138(29):9037-40.
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