Thermolysin( —— )

Catalog No. M36645 CAS No. 9073-78-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Thermolysin
Note

Research use only, not for human use.
Brief Description

Thermolysin is an extracellular metalloendopeptidase from Bacillus thermolysinophilus that selectively catalyzes short peptides.
Description

Thermolysin (EC 3.4.24.27) (TML) is a thermostable neutral metalloproteinase enzyme secreted by the Gram-positive bacteria Bacillus thermoproteolyticus. Thermolysin catalyzes the hydrolysis of peptide bonds containing hydrophobic residues.Optimal pH: 8.0. Considerably stable from pH 5 to 9.5.Optimal temperature : 70 °C
In Vitro

——
In Vivo

Animal Model:Spontaneously hypertensive rats (SHR) rats Dosage:50 mg/kg Administration:Oral administration (p.o.), once Result:Lowered systolic blood pressure in SHR rats, with maximal reduction by 22 mm in systolic blood pressure being observed 6 h after administration.
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Endogenous Metabolite
Research Area

——
Indication

——

1. Bertusvan den Burg, et al. Chapter 111 - Thermolysin and Related Bacillus Metallopeptidases.

Calculator

molnova catalog