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KDM4C-IN-1
CAS No. 52348-60-4
KDM4C-IN-1( —— )
Catalog No. M35451 CAS No. 52348-60-4
KDM4C-IN-1 is a selective and potent KDM4C inhibitor (IC50: 8 nM) with potential anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 150 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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Biological Information
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Product NameKDM4C-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionKDM4C-IN-1 is a selective and potent KDM4C inhibitor (IC50: 8 nM) with potential anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.
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DescriptionKDM4C-IN-1 (Compound 4d) is a potent KDM4C inhibitor with an IC50 of 8 nM. KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells with IC50s of 0.8 μM and 1.1 μM, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorHistone Demethylase
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Research Area——
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Indication——
Chemical Information
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CAS Number52348-60-4
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Formula Weight298.3
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Molecular FormulaC15H14N4O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 3 mg/mL (10.02 mM )
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SMILESCOc1ccc(cc1)-c1nn(C)c2nc(=O)n(C)c(=O)c2n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Vatroslav Letfus, et al. Rational design, synthesis and biological profiling of new KDM4C inhibitors. Bioorg Med Chem. 2020 Jan 1;28(1):115128. ?
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