Hematin

CAS No. 15489-90-4

Hematin( Ferrihemate | Ferriheme | Ferriheme hydroxide | Ferrihemic acid )

Catalog No. M27159 CAS No. 15489-90-4

Hematin is an iron-containing porphyrin. It is used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Hematin
  • Note
    Research use only, not for human use.
  • Brief Description
    Hematin is an iron-containing porphyrin. It is used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.
  • Description
    Hematin is an iron-containing porphyrin. It is used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.
  • In Vitro
    Hematin (0.01 mg/ml) inhibits the clotting of bovine fibrinogen (1.3 to 2.6 mg/ml) by bovine thrombin (0.12 U/ml) and inhibits the hydrolysis of a synthetic substrate by human thrombin.Hematin (0.035 mg/ml) reduces VIII:C activity from 0.88 to 0.40 U/ml.Hematin (0.05 mg/ml) inhibits the activation of VIII:C by thrombin (0.04 U/ml).Hematin (0.09 mg/ml) inhibits the hydrolysis of a synthetic substrate by plasmin.
  • In Vivo
    Hematin (i.v.; single injection) suppressed porphyrin production in SD rat (weighing 160-205 g).
  • Synonyms
    Ferrihemate | Ferriheme | Ferriheme hydroxide | Ferrihemic acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Antifection| VEGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    15489-90-4
  • Formula Weight
    633.5
  • Molecular Formula
    C34H33FeN4O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 1.43 mg/mL (2.26 mM)
  • SMILES
    CC1=C(C=C2C(C)=C(C=C)C3=[N]2[Fe]45(O)N6C(C(C)=C(C=C)C6=C7)=C3)N4C(C=C8[N]5=C7C(C)=C8CCC(O)=O)=C1CCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Antifungal activity of lariciresinol derived from Sambucus williamsii and their membrane-active mechanisms in Candida albicans.Biochem Biophys Res Commun. 2011 Jul 8;410(3):489-93.
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