Dihydrorhodamine 123( DHR 123 )

Catalog No. M23294 CAS No. 109244-58-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Dihydrorhodamine 123
Note

Research use only, not for human use.
Brief Description

Dihydrorhodamine 123 is a fluorescent probe.
Description

Dihydrorhodamine 123 is a fluorescent probe (λex=488 nm, λem=525 nm).
In Vitro

In the presence of 10 μM Dihydrorhodamine 123 (DHR 123) the stimulation of the neutrophil NADPH oxidase by the addition of 50 nM phorbol 12-myristate 13-acetat (PMA) resultes in an increase in the rate of rhodamine generation. The fluorescent intensity of the cells, in the presence of 10 μM Dihydrorhodamine 123, increases with time following the addition of 50 nM PMA. In the presence of 10 μM Dihydrorhodamine 123, induced HL60 cells show a sustained increase in fluorescence following the addition of 50 nM PMA.
In Vivo

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Synonyms

DHR 123
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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1.Lydia M. Henderson et al. Dihydrorhodamine 123: a fluorescent probe for superoxide generation? Eur.J.Biochem. 217, 973-980.

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