Urolithin B( —— )

Catalog No. M22685 CAS No. 1139-83-9

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HNMR

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MSDS

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Product Name

Urolithin B
Note

Research use only, not for human use.
Brief Description

Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
Description

Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
In Vitro

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In Vivo

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Synonyms

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Pathway

Apoptosis
Target

NF-κB
Recptor

NF-κB| JNK| ERK| Akt| AMPK| Human Endogenous Metabolite
Research Area

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Indication

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1. Lee G, et al. Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia. Phytomedicine. 2019 Mar 1;55:50-57.

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