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BAY 2416964
CAS No. 2242464-44-2
BAY 2416964( —— )
Catalog No. M22445 CAS No. 2242464-44-2
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
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| 5MG | 73 | In Stock |
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| 10MG | 117 | In Stock |
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| 25MG | 235 | In Stock |
|
| 50MG | 346 | In Stock |
|
| 100MG | 554 | In Stock |
|
| 200MG | 777 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBAY 2416964
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NoteResearch use only, not for human use.
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Brief DescriptionBAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
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DescriptionBAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 192, IC50: 341 nM). It has the potential for cancer treatment.BAY 2416964 induces AHR-regulated gene CYP1A1 expression in human monocytic U937 cells (IC50: 4.3 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAryl hydrocarbon receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2242464-44-2
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Formula Weight387.82
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Molecular FormulaC18H18ClN5O3
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL (644.63 mM; Need ultrasonic)
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SMILESC[C@@H](CO)NC(=O)c1cc(nn(-c2cnn(C)c2)c1=O)-c1ccc(Cl)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ilona GUTCHER, et al. 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer. WO2018146010A1.
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