Hexadimethrine bromide( 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide )

Catalog No. M22124 CAS No. 28728-55-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Hexadimethrine bromide
Note

Research use only, not for human use.
Brief Description

Hexadimethrine bromide is a synthetic polymer which agglutinates red blood cells, and used as a heparin antagonist.Hexadimethrine bromide inhibits human mesenchymal stem cell proliferation during lentiviral transduction.
Description

Hexadimethrine bromide is a synthetic polymer which agglutinates red blood cells, and used as a heparin antagonist.Hexadimethrine bromide inhibits human mesenchymal stem cell proliferation during lentiviral transduction. Hexadimethrine bromide is considered non-toxic at low concentrations, but has been found to negatively affect cell proliferation in some cell types at concentrations greater than 10 μg/mL. Trypsinized cells exposed to Hexadimethrine bromide are visibly larger in size when viewed under the microscope.
In Vitro

Hexadimethrine bromide inhibits human mesenchymal stem cell proliferation during lentiviral transduction. Hexadimethrine bromide is considered non-toxic at low concentrations, but has been found to negatively affect cell proliferation in some cell types at concentrations greater than 10 μg/mL. Trypsinized cells exposed to Hexadimethrine bromide are visibly larger in size when viewed under the microscope.
In Vivo

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Synonyms

1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide
Pathway

Others
Target

Other Targets
Recptor

heparin
Research Area

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Indication

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CAS Number

28728-55-4
Formula Weight

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Molecular Formula

(C13H30N2)n.2Br
Purity

>98% (HPLC)
Solubility

H2O:125 mg/mL (309.20 mM);DMSO:4.5 mg/mL (Need ultrasonic and warming)
SMILES

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Chemical Name

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1.Lin P, et al. Polybrene inhibits human mesenchymal stem cell proliferation during lentiviral transduction. PLoS One. 2011;6(8):e23891.

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