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D-tetrahydropalmatine

CAS No. 3520-14-7

D-tetrahydropalmatine( —— )

Catalog No. M21452 CAS No. 3520-14-7

D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    D-tetrahydropalmatine
  • Note
    Research use only, not for human use.
  • Brief Description
    D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.
  • Description
    D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3520-14-7
  • Formula Weight
    355.4
  • Molecular Formula
    C21H25NO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (140.67 mM)
  • SMILES
    COc(ccc(C1)c2CN(CC3)[C@H]1c(cc1OC)c3cc1OC)c2OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tu M Sun S Wang K et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity[J]. Toxicology 2013 311(3):225-230.
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