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D-tetrahydropalmatine

CAS No. 3520-14-7

D-tetrahydropalmatine( —— )

Catalog No. M21452 CAS No. 3520-14-7

D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 56 In Stock
2MG 35 In Stock
5MG 55 In Stock
10MG 93 In Stock
25MG 181 In Stock
50MG 267 In Stock
100MG 384 In Stock
200MG 547 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    D-tetrahydropalmatine
  • Note
    Research use only, not for human use.
  • Brief Description
    D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.
  • Description
    D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3520-14-7
  • Formula Weight
    355.4
  • Molecular Formula
    C21H25NO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (140.67 mM)
  • SMILES
    COc(ccc(C1)c2CN(CC3)[C@H]1c(cc1OC)c3cc1OC)c2OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tu M Sun S Wang K et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity[J]. Toxicology 2013 311(3):225-230.
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