Pargyline hydrochloride

Research use only, not for human use.

Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension.

Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension.

Cell Proliferation Assay Cell Line:LNCaP-LN3 cells Concentration:0.5 mM, 1 mM, 1.5 mM or 2 mM Incubation Time:24 hours, 48 hours, 72 hours, 96 hours or 120 hours Result:Inhibited the proliferation of prostate cancer cells in a time- and dose-dependent manner.Cell Cycle Analysis Cell Line:LNCaP-LN3 cells Concentration:0.5 mM, 2 mM Incubation Time:24 hours, 48 hours Result:The S phase ratio of the cells was decreased, while their G1 phase ratio was increased.Apoptosis Analysis Cell Line:LNCaP-LN3 cells Concentration:0.5 mMIncubation Time:24 hours Result:Increased the apoptotic cells.Western Blot Analysis Cell Line:LNCaP-LN3 cells Concentration:2 mM Incubation Time:48 hours Result:Induced an increase of cytochrome c and a decrease of caspase-3.

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NSC 43798

Metabolic Enzyme/Protease

MAO

MAO

Neurological Disease

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306-07-0

195.69

C11H14NCl

>98% (HPLC)

DMSO: 38 mg/mL

CN(CC#C)CC1=CC=CC=C1.Cl

N-benzyl-N-methylprop-2-yn-1-amine;hydrochloride

(-20℃)

With Ice Pack

≥ 2 years