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LLP2A
CAS No. 874148-50-2
LLP2A( —— )
Catalog No. M16358 CAS No. 874148-50-2
LLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameLLP2A
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NoteResearch use only, not for human use.
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Brief DescriptionLLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM.
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DescriptionLLP2A is a high-affinity, selective peptidomimetic ligand of α4β1 integrin with IC50 of 2 pM; shows no binding affinity for α2β1, α6β1, αLβ2 and αMβ2 integrins; can be used to image α4β1-expressing lymphomas with high sensitivity and specificity when conjugated to a near infrared fluorescent dye in a mouse xenograft model.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorIntegrin
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Research Area——
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Indication——
Chemical Information
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CAS Number874148-50-2
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Formula Weight810.953
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Molecular FormulaC43H54N8O8
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(S)-6-((1-carbamoylcyclohexyl)amino)-6-oxo-5-((S)-6-((E)-3-(pyridin-3-yl)acrylamido)-2-(2-(4-(3-(o-tolyl)ureido)phenyl)acetamido)hexanamido)hexanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Peng L, et al. Nat Chem Biol. 2006 Jul;2(7):381-9.
2. Beaino W, et al. J Nucl Med. 2014 Nov;55(11):1856-63.
3. Soodgupta D, et al. J Nucl Med. 2016 Apr;57(4):640-5.
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