K00546

CAS No. 443798-47-8

K00546 ( K 00546 )

Catalog No. M14518 CAS No. 443798-47-8

K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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100MG 1638 Get Quote
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Biological Information

  • Product Name
    K00546
  • Note
    Research use only, not for human use.
  • Brief Description
    K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.
  • Description
    K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.
  • Synonyms
    K 00546
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    CLK
  • Recptor
    CLK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    443798-47-8
  • Formula Weight
    425.43
  • Molecular Formula
    C15H13F2N7O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1=CC(=C(C(=C1)F)NC(=S)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F
  • Chemical Name
    5-amino-N-(2,6-difluorophenyl)-3-((4-sulfamoylphenyl)amino)-1H-1,2,4-triazole-1-carbothioamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fedorov O, et al. Chem Biol. 2011 Jan 28;18(1):67-76.
2. Prak K, et al. Biochemistry. 2016 Jan 26;55(3):608-17.
molnova catalog
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