Cart
sales@molnova.com
K00546
CAS No. 443798-47-8
K00546 ( K 00546 )
Catalog No. M14518 CAS No. 443798-47-8
K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 1062 | Get Quote |
|
| 100MG | 1638 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameK00546
-
NoteResearch use only, not for human use.
-
Brief DescriptionK00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.
-
DescriptionK00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.
-
SynonymsK 00546
-
PathwayCell Cycle/DNA Damage
-
TargetCLK
-
RecptorCLK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number443798-47-8
-
Formula Weight425.43
-
Molecular FormulaC15H13F2N7O2S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC1=CC(=C(C(=C1)F)NC(=S)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F
-
Chemical Name5-amino-N-(2,6-difluorophenyl)-3-((4-sulfamoylphenyl)amino)-1H-1,2,4-triazole-1-carbothioamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Fedorov O, et al. Chem Biol. 2011 Jan 28;18(1):67-76.
2. Prak K, et al. Biochemistry. 2016 Jan 26;55(3):608-17.
2. Prak K, et al. Biochemistry. 2016 Jan 26;55(3):608-17.
molnova catalog
related products
-
Leucettamine B
Leucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).
-
KuWal151
KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively.
-
CLK2 inhibitor Indaz...
CLK2 inhibitor Indazole1 is a novel potent, selective inhibitor of CLK2 with IC50 of 2.7 nM.
