Cart
sales@molnova.com
G150
CAS No. 2369751-30-2
G150 ( —— )
Catalog No. M24083 CAS No. 2369751-30-2
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 260 | In Stock |
|
| 10MG | 410 | In Stock |
|
| 25MG | 678 | In Stock |
|
| 50MG | 954 | In Stock |
|
| 100MG | 1287 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameG150
-
NoteResearch use only, not for human use.
-
Brief DescriptionG150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.
-
DescriptionG150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptordsDNA/cGAS;h-cGAS
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2369751-30-2
-
Formula Weight391.3
-
Molecular FormulaC18H16Cl2N4O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:120 mg/mL (306.71 mM; Need ultrasonic)
-
SMILESNc(cc1)ncc1-c(c1c2[nH]c(CC3)c1CN3C(CO)=O)cc(Cl)c2Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Lama L, et al. Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nat Commun. 2019 May 21;10(1):2261.
molnova catalog
related products
-
Fosifloxuridine nafa...
NUC-3373 (Fosifloxuridine nafalbenamide), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.NUC-3373 has anticancer activity.
-
Pyridostatin Trihydr...
Pyridostatin hydrochloride is a G-quadruplexe stabilizer with a Kd of 490 nM.
-
PNR-7-02
PNR-7-02 is a specific inhibitor of human DNA Polymerase η (hPol η) with IC50 of 8 uM.
