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BILH-434
CAS No. 760169-28-6
BILH-434( BILH434 )
Catalog No. M15887 CAS No. 760169-28-6
BILH-434 is a potent HPV11 E1/E2/DNA complex inhibitor that binds to the transactivation domain (TAD) of E2 protein with a Kd of 40 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBILH-434
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NoteResearch use only, not for human use.
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Brief DescriptionBILH-434 is a potent HPV11 E1/E2/DNA complex inhibitor that binds to the transactivation domain (TAD) of E2 protein with a Kd of 40 nM.
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DescriptionBILH-434 is a potent HPV11 E1/E2/DNA complex inhibitor that binds to the transactivation domain (TAD) of E2 protein with a Kd of 40 nM, has an IC50 of 180 nM in the E1-E2-ori complex formation assay.
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In Vitro——
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In Vivo——
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SynonymsBILH434
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PathwayMicrobiology/Virology
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TargetHPV
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RecptorHPV
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Research Area——
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Indication——
Chemical Information
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CAS Number760169-28-6
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Formula Weight608.446
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Molecular FormulaC29H19Cl2N3O6S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(2R,3'R,4'S,5'R)-5'-(3,4-dichlorophenyl)-5-methyl-1,3-dioxo-4'-[[4-(thiadiazol-4-yl)phenyl]carbamoyl]spiro[indene-2,2'-oxolane]-3'-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14.
2. Wang Y, et al. J Biol Chem. 2004 Feb 20;279(8):6976-85.
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