Cart
sales@molnova.com
Atractylodin
CAS No. 55290-63-6
Atractylodin( Atractydin )
Catalog No. M18797 CAS No. 55290-63-6
Atractylodin has high lipase inhibitory activity (IC5:39.12?μM); Atractylodin possesses strong repellency activities against T. castaneum adults (LD50: 1.83?μg/cm).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 76 | In Stock |
|
| 10MG | 125 | In Stock |
|
| 25MG | 246 | In Stock |
|
| 50MG | 370 | In Stock |
|
| 100MG | 537 | In Stock |
|
| 500MG | 1161 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAtractylodin
-
NoteResearch use only, not for human use.
-
Brief DescriptionAtractylodin has high lipase inhibitory activity (IC5:39.12?μM); Atractylodin possesses strong repellency activities against T. castaneum adults (LD50: 1.83?μg/cm).
-
DescriptionAtractylodin has high lipase inhibitory activity (IC5:39.12?μM); Atractylodin possesses strong repellency activities against T. castaneum adults (LD50: 1.83?μg/cm). The repellency of Atractylodin (0.63?μg/cm) can achieve >90%.
-
In VitroCell Viability Assay Cell Line:NCM460, SW480, HCT116 Concentration:1, 10, 25, 50, 100 μM Incubation Time:24 h Result:Decreased viability at a concentration of 100 μM in HCT116 cells.Western Blot Analysis Cell Line:HCT116 Concentration:50 μM Incubation Time:1 h Result:Inhibited TNF-α-induced phosphorylation of NF-κB p65.
-
In VivoAnimal Model:DSS-Induced Colitis Mouse Model Dosage:40 mg/kg Administration:i.p.Result:Reduced colitis symptoms and increased survival rate.Animal Model:NAFLD mice model Dosage:20, 40, 80 mg/kg Administration:i.g.Result:Reduced the release of ALT, AST, ROS and MDA.
-
SynonymsAtractydin
-
PathwayApoptosis
-
TargetNF-κB
-
Recptorlipase
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number55290-63-6
-
Formula Weight182.22
-
Molecular FormulaC13H10O
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 6 mg/mL 32.93 mM; H2O : < 0.1 mg/mL
-
SMILESC/C=C/C#CC#C/C=C/c1ccco1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Tao J, et al. Zhongguo Zhong Yao Za Zhi. 2011 Jan;36(1):27-31.
molnova catalog
related products
-
CL075
CL075 (3M002) is a selective TLR8 agonist with immunomodulatory activity, triggering the MyD88-dependent signaling pathway and activating NF-κB and IRF7 to elicit the production of inflammatory cytokines and type I interferon (IFN).
-
SR12460
SR12460 (SR-12460) is a novel NF-κB essential modulator (NEMO)-binding domain (NBD) mimetic for inhibiting IKK/NF-κB activation.
-
ABD328
ABD328 (ABD-328) is an orally active, small molecule inhibitor of RANKL and TNF signalling that inhibits inflammation in vivo.
