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Atglistatin

CAS No. 1469924-27-3

Atglistatin ( Atglistatin )

Catalog No. M12010 CAS No. 1469924-27-3

Atglistatin is a highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL) with anIC50of ~0.7 μM for inhibition of lipolysis in vitro, but no toxicity up to a concentration of 50 μM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Atglistatin
  • Note
    Research use only, not for human use.
  • Brief Description
    Atglistatin is a highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL) with anIC50of ~0.7 μM for inhibition of lipolysis in vitro, but no toxicity up to a concentration of 50 μM.
  • Description
    Atglistatin is a highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL) with anIC50of ~0.7 μM for inhibition of lipolysis in vitro, but no toxicity up to a concentration of 50 μM.
  • Synonyms
    Atglistatin
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Lipase
  • Recptor
    ATGL
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1469924-27-3
  • Formula Weight
    283.37
  • Molecular Formula
    C17H21N3O
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 4 mg/mL (14.11 mM); DMSO: 57 mg/mL (201.15 mM)
  • SMILES
    CN(C1=CC=C(C=C1)C2=CC(NC(N(C)C)=O)=CC=C2)C
  • Chemical Name
    3-(4'-(dimethylamino)-[1,1'-biphenyl]-3-yl)-1,1-dimethylurea

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mayer N, et al. Nat Chem Biol. 2013, 9(12), 785-787.
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