
Amino-PEG11-amine
CAS No. 479200-82-3
Amino-PEG11-amine( —— )
Catalog No. M24428 CAS No. 479200-82-3
Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
10MG | 50 | In Stock |
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25MG | 78 | In Stock |
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50MG | 111 | In Stock |
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100MG | 158 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameAmino-PEG11-amine
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NoteResearch use only, not for human use.
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Brief DescriptionAmino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.
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DescriptionAmino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPEGs
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Research Area——
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Indication——
Chemical Information
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CAS Number479200-82-3
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Formula Weight544.68
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Molecular FormulaC24H52N2O11
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESNCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Shan M, et al. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. ACS Chem Biol. 2013 Apr 19;8(4):707-15.
molnova catalog



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