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AT-121
CAS No. 2099681-31-7
AT-121( —— )
Catalog No. M34966 CAS No. 2099681-31-7
AT-121 is a dual μ-opioid and neuropeptide receptor partial agonist (Kis 16.49 and 3.67 nM, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 532 | Get Quote |
|
| 5MG | 787 | Get Quote |
|
| 10MG | 1074 | Get Quote |
|
| 25MG | 1463 | Get Quote |
|
| 50MG | 1822 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 500MG | 4410 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAT-121
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NoteResearch use only, not for human use.
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Brief DescriptionAT-121 is a dual μ-opioid and neuropeptide receptor partial agonist (Kis 16.49 and 3.67 nM, respectively).
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DescriptionAT-121 is a bifunctional nociception and mu opioid receptor agonist, with Kis of 3.67 and 16.49 nM, respectively. AT-121 is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects.
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In Vitro——
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In VivoAT-121 (0.003-0.03 mg/kg; s.c.) produces potent antinociceptive effect.Animal Model:Adult male and female rhesus monkeysDosage:0.003-0.03 mg/kg Administration:Subcutaneous Result:Produced antinociceptive effects against an acute noxious stimulus, 50 °C water, in a dose-dependent.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetOpioid Receptor
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RecptorOpioid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2099681-31-7
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Formula Weight462.65
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Molecular FormulaC24H38N4O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1C2(C=3C(CN1CCNS(N)(=O)=O)=CC=CC3)CCN(CC2)[C@@H]4CC[C@H]([C@H](C)C)CC4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ding H, Kiguchi N, Yasuda D, et al. A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates. Sci Transl Med. 2018;10(456):eaar3483. doi:10.1126/scitranslmed.aar3483?
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