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A-803467

CAS No. 944261-79-4

A-803467 ( A-803467; A 803467; A803467 )

Catalog No. M16765 CAS No. 944261-79-4

A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM, blocks tetrodotoxin-resistant currents.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    A-803467
  • Note
    Research use only, not for human use.
  • Brief Description
    A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM, blocks tetrodotoxin-resistant currents.
  • Description
    A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM, blocks tetrodotoxin-resistant currents, exhibits >100-fold selectivity against human NaV1.2, NaV1.3, NaV1.5, and NaV1.7.
  • Synonyms
    A-803467; A 803467; A803467
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Na(V1.8) channel
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    944261-79-4
  • Formula Weight
    357.79
  • Molecular Formula
    C19H16ClNO4
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 11 mg/mL (30.74 mM); DMSO: 72 mg/mL (201.23 mM)
  • SMILES
    O=C(C1=CC=C(C2=CC=C(Cl)C=C2)O1)NC3=CC(OC)=CC(OC)=C3
  • Chemical Name
    5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furancarboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jarvis MF, et al. Proc Natl Acad Sci U S A, 2007, 104(20), 8520-8525.
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