(Z)-Guggulsterone( —— )

Catalog No. M24353 CAS No. 39025-23-5

(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	118	In Stock
25MG	235	In Stock
50MG	352	In Stock
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Biological Information

Product Name

(Z)-Guggulsterone
Note

Research use only, not for human use.
Brief Description

(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Description

(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Synonyms

——
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Akt
Recptor

Akt;VEGF-R2
Research Area

——
Indication

——

Chemical Information

CAS Number

39025-23-5
Formula Weight

312.5
Molecular Formula

C21H28O2
Purity

>98% (HPLC)
Solubility

DMSO:10 mg/mL?(32.01 mM;?ultrasonic and warming and heat to 60°C)
SMILES

C/C=C/1\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Xiao D, et al. z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo. Mol Cancer Ther. 2008 Jan;7(1):171-80.

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