(Z)-Guggulsterone

CAS No. 39025-23-5

(Z)-Guggulsterone( —— )

Catalog No. M24353 CAS No. 39025-23-5

(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 82 In Stock
10MG 118 In Stock
25MG 235 In Stock
50MG 352 In Stock
100MG 528 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    (Z)-Guggulsterone
  • Note
    Research use only, not for human use.
  • Brief Description
    (Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
  • Description
    (Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Akt
  • Recptor
    Akt;VEGF-R2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    39025-23-5
  • Formula Weight
    312.5
  • Molecular Formula
    C21H28O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mg/mL?(32.01 mM;?ultrasonic and warming and heat to 60°C)
  • SMILES
    C/C=C/1\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xiao D, et al. z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo. Mol Cancer Ther. 2008 Jan;7(1):171-80.
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