(Z)-Guggulsterone
CAS No. 39025-23-5
(Z)-Guggulsterone( —— )
Catalog No. M24353 CAS No. 39025-23-5
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
5MG | 82 | In Stock |
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10MG | 118 | In Stock |
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25MG | 235 | In Stock |
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50MG | 352 | In Stock |
|
100MG | 528 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product Name(Z)-Guggulsterone
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NoteResearch use only, not for human use.
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Brief Description(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
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Description(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetAkt
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RecptorAkt;VEGF-R2
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Research Area——
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Indication——
Chemical Information
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CAS Number39025-23-5
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Formula Weight312.5
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Molecular FormulaC21H28O2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mg/mL?(32.01 mM;?ultrasonic and warming and heat to 60°C)
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SMILESC/C=C/1\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Marein
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway.
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TAS-117
TAS-117 is a highly selective, non-ATP competitive pan-Akt inhibitor with IC50 of 4.8/1.6/44 nM for Akt1/Akt2/Akt3 respectively.
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Arnicolide D
Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.