(Z)-Guggulsterone
CAS No. 39025-23-5
(Z)-Guggulsterone( —— )
Catalog No. M24353 CAS No. 39025-23-5
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 82 | In Stock |
|
10MG | 118 | In Stock |
|
25MG | 235 | In Stock |
|
50MG | 352 | In Stock |
|
100MG | 528 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product Name(Z)-Guggulsterone
-
NoteResearch use only, not for human use.
-
Brief Description(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
-
Description(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
-
Synonyms——
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetAkt
-
RecptorAkt;VEGF-R2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number39025-23-5
-
Formula Weight312.5
-
Molecular FormulaC21H28O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mg/mL?(32.01 mM;?ultrasonic and warming and heat to 60°C)
-
SMILESC/C=C/1\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Xiao D, et al. z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo. Mol Cancer Ther. 2008 Jan;7(1):171-80.
molnova catalog
related products
-
Afuresertib
A potent, selective, ATP-competitive pan-AKT inhibitor with biochemical IC50 of 0.08/2/2.6 nM for AKT1/2/3.
-
A-674563 2HCl(552325...
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.A-674563 reduces phosphorylation of Akt downstream targets in cells and slows proliferation of tumor cells in vitro (EC50: 0.4 μM) [1]. A563 (0-10 μM) markedly decreases GSK3 and MDM2 phosphorylation in STS cells.
-
BAY-1125976
A potent and highly selective, allosteric AKT1/2 inhibitor with IC50 of 5.2/18 nM at 10 uM ATP.